What are common side effects associated with NSAIDs?

What are common side effects associated with NSAIDs?

• A. GI upset, bleeding, tinnitus
• B. Fatigue, nausea, dizziness
• C. Headaches, rash, sleep disturbances
• D. Constipation, hypertension, fever

Answer: (A)

The selection of GI upset, bleeding, and tinnitus as common side effects associated with nonsteroidal anti-inflammatory drugs (NSAIDs) is well-founded. NSAIDs, such as ibuprofen and naproxen, are widely used for their analgesic and anti-inflammatory properties. Gastrointestinal upset is a prevalent issue due to the way NSAIDs inhibit cyclooxygenase (COX) enzymes, which not only reduce inflammation and pain but also lead to decreased production of protective gastric mucosa. This can result in symptoms like stomach pain, nausea, or dyspepsia. Moreover, these drugs can also cause gastrointestinal bleeding, especially in long-term use or in individuals with certain risk factors such as older age or a history of ulcers, as they can erode the gastric lining. Tinnitus, or ringing in the ears, can occur with higher doses of some NSAIDs. This effect is still not thoroughly understood, but it is recognized as a potential side effect. Other options listed may contain symptoms that can occur with different classes of medications or conditions but are not generally recognized as common side effects of NSAIDs. For instance, fatigue and dizziness may be associated with numerous medications or illnesses but are not characteristic of NSAID use specifically. Understanding these

The selection of GI upset, bleeding, and tinnitus as common side effects associated with nonsteroidal anti-inflammatory drugs (NSAIDs) is well-founded. NSAIDs, such as ibuprofen and naproxen, are widely used for their analgesic and anti-inflammatory properties.

Gastrointestinal upset is a prevalent issue due to the way NSAIDs inhibit cyclooxygenase (COX) enzymes, which not only reduce inflammation and pain but also lead to decreased production of protective gastric mucosa. This can result in symptoms like stomach pain, nausea, or dyspepsia. Moreover, these drugs can also cause gastrointestinal bleeding, especially in long-term use or in individuals with certain risk factors such as older age or a history of ulcers, as they can erode the gastric lining.

Tinnitus, or ringing in the ears, can occur with higher doses of some NSAIDs. This effect is still not thoroughly understood, but it is recognized as a potential side effect.

Other options listed may contain symptoms that can occur with different classes of medications or conditions but are not generally recognized as common side effects of NSAIDs. For instance, fatigue and dizziness may be associated with numerous medications or illnesses but are not characteristic of NSAID use specifically. Understanding these